Fig. 1 · Structure

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PARP10/15-IN-2

PARP10/PARP15 Inhibitor

PARP10/15-IN-2 is a potent dual inhibitor of PARP10 and PARP15, exhibiting IC50 values of 0.15 µM and 0.37 µM, respectively. This compound has demonstrated the ability to penetrate cellular membranes and effectively rescue cells from apoptosis. PARP10/15-IN-2 serves as a valuable tool for research into cell survival mechanisms and the modulation of PARP-related signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2892064-99-0
Applications PARP10/PARP15 Inhibitor
Formula C15H11FN2O3
Molecular Weight 286.26
SMILES
O=C1NNC(C2=C1C=CC(OCC3=CC=CC=C3F)=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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