PARP10-IN-2 is a selective inhibitor of the mono-ADP-ribosyltransferase PARP10, exhibiting an IC50 of 3.64 µM in human PARP10 assays. This compound also effectively inhibits PARP2 and PARP15, with IC50 values of 27 µM and 11 µM, respectively. PARP10-IN-2 is valuable for research applications focusing on cellular processes influenced by ADP-ribosylation and has potential implications in cancer and neurodegenerative disease studies.
PARP10-IN-2 is a selective inhibitor of the mono-ADP-ribosyltransferase PARP10, exhibiting an IC50 of 3.64 µM in human PARP10 assays. This compound also effectively inhibits PARP2 and PARP15, with IC50 values of 27 µM and 11 µM, respectively. PARP10-IN-2 is valuable for research applications focusing on cellular processes influenced by ADP-ribosylation and has potential implications in cancer and neurodegenerative disease studies.
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