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PARP14 inhibitor 2

PARP14 Inhibitor

PARP14 Inhibitor 2 is a highly selective inhibitor targeting PARP14 with an IC50 value of less than 30 nM. This compound effectively inhibits the mono-ADP-ribosyltransferase activity of PARP14, thereby modulating signaling pathways associated with IFN-γ and IL-4. By reversing protumor macrophage polarization and inhibiting pro-inflammatory responses, PARP14 Inhibitor 2 holds promise for the investigation of diseases related to PARP14, including tumors, atopic dermatitis, and autoimmune disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3064731-00-3
Applications	PARP14 Inhibitor
Formula	C₂₅H₃₂FN₃O₄S
Molecular Weight	489.60
SMILES	O=C1N=C(CSC2CCOCC2)NC3=CC(OCC45CCC(CC4)(CC5)NC(C)=O)=CC(F)=C13

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.