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PARP7-IN-21

PARP7 Inhibitor

PARP7-IN-21 is a potent inhibitor of PARP7, demonstrating an IC50 of less than 10 nM. This compound effectively interferes with the activity of PARP7, which is involved in the regulation of cellular processes such as DNA repair and signaling pathways related to stress response. PARP7-IN-21 is valuable for research applications focused on cancer biology, neurodegenerative diseases, and other conditions associated with PARP7 dysregulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034666-02-6
Applications	PARP7 Inhibitor
Formula	C₂₄H₂₆F₃N₇O₂
Molecular Weight	501.50
SMILES	O=C1NN=C2C(CC[C@H]2N3C[C@](C(N4CCN(C5=CC=C(C#N)C=N5)CC4)=O)(C)CC3)=C1C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.