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PARP7-IN-23

PARP7 Inhibitor

PARP7-IN-23 is a potent inhibitor of Poly(ADP-ribose) polymerase 7 (PARP7) with an EC50 of 0.915 nM for phosphorylated STAT1 (pSTAT1) in NCI-H1373 cells. This compound demonstrates significant inhibitory activity, which positions it as a valuable tool for cancer research, particularly in studies involving STAT1 signaling pathways and therapeutic interventions targeting PARP7.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3071875-24-3
Applications	PARP7 Inhibitor
Formula	C₂₇H₂₂F₇N₅O₃
Molecular Weight	597.48
SMILES	O=C1NN=CC(O[C@@H]2C[C@H](CN3C(C(C(F)=C(F)C(C4=NC=C(C(F)(F)C)C=N4)=C5)=C5C=C3)=O)CCC2)=C1C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.