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PAT1inh-A0030

PAT1 (SLC26A6) Inhibitor

PAT1inh-A0030 is a selective inhibitor of PAT1 (SLC26A6), exhibiting an IC50 of 1.0 μM. This compound effectively inhibits fluid absorption in the ileum of both wild-type and cystic fibrosis (CF) mouse models (CftrdelF508/delF508) in a closed-loop intestinal fluid absorption assay. PAT1inh-A0030 serves as a valuable tool for investigating the pathophysiology of intestinal diseases associated with cystic fibrosis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1030097-65-4
Applications	PAT1 (SLC26A6) Inhibitor
Formula	C₁₇H₁₈N₄O₃
Molecular Weight	326.35
SMILES	O=C(C1=NC(N(CC2=CC=CC=C2)C)=C3C(ON=C3C)=N1)OCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.