Fig. 1 · Structure
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Patisiran sodium
Transthyretin Inhibitor
Patisiran sodium is a double-stranded small interfering RNA that targets a specific sequence within the messenger RNA of transthyretin (TTR). It effectively inhibits the hepatic synthesis of both mutant and wild-type TTR. This reagent is primarily used in research applications related to hereditary TTR amyloidosis, providing valuable insights into the disorder's underlying mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1386913-72-9 |
| Applications | Transthyretin Inhibitor |
| Molecular Weight | 13424 (free acid) |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.