Fig. 1 · Structure
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Paynantheine
5-HT Agonist
Paynantheine is an alkaloid primarily recognized for its agonistic activity at the 5-HT1A and 5-HT2B receptors. This compound exhibits notable antinociceptive properties, demonstrated by its ability to induce lower lip retraction in rodent models. Its mechanism of action makes Paynantheine a valuable tool for research into analgesic pathways and the modulation of serotonin receptors in pain studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 4697-66-9 |
| Applications | 5-HT Agonist |
| Formula | C23H28N2O4 |
| Molecular Weight | 396.48 |
| SMILES | COC1=C2C3=C(NC2=CC=C1)[C@@]4([H])N(C[C@@H]([C@H](C4)/C(C(OC)=O)=C\OC)C=C)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.