Pazopanib-13C,d3 is a stable isotope-labeled form of Pazopanib, a potent multi-target inhibitor primarily affecting VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with respective IC50 values of 10, 30, 47, 84, 74, 140, and 146 nM. This isotope-labeled compound is valuable in pharmacokinetic studies and metabolic research applications, facilitating the exploration of drug metabolism and distribution in biological systems. Ideal for use in quantitative analysis and imaging studies, Pazopanib-13C,d3 enhances the understanding of tumor angiogenesis and targeted cancer therapies.
Pazopanib-13C,d3 is a stable isotope-labeled form of Pazopanib, a potent multi-target inhibitor primarily affecting VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with respective IC50 values of 10, 30, 47, 84, 74, 140, and 146 nM. This isotope-labeled compound is valuable in pharmacokinetic studies and metabolic research applications, facilitating the exploration of drug metabolism and distribution in biological systems. Ideal for use in quantitative analysis and imaging studies, Pazopanib-13C,d3 enhances the understanding of tumor angiogenesis and targeted cancer therapies.
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