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Pazufloxacin-d4

Stable Isotope

Pazufloxacin-d4 is a deuterated derivative of the fluoroquinolone antimicrobial agent Pazufloxacin. This compound specifically targets DNA gyrase, demonstrating inhibitory activity with IC50 values of 0.88 μg/mL against E. coli and 1.9 μg/mL against P. aeruginosa. Pazufloxacin-d4 showcases broad-spectrum antimicrobial efficacy, with MIC90 values ranging between 0.025 to 100 μg/mL against various Gram-positive and Gram-negative bacteria, including non-fermenting pathogens and anaerobes. This reagent is suitable for investigating systemic and lung infections, as well as urinary tract infections and Legionella pneumonia in research contexts.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1346602-96-7
Applications	Stable Isotope
Formula	C₁₆H₁₁D₄FN₂O₄
Molecular Weight	322.32
Synonyms	T3761-d4
SMILES	O=C1C2=CC(F)=C(C3(C([2H])([2H])C3([2H])[2H])N)C4=C2N(C=C1C(O)=O)[C@@H](C)CO4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.