Fig. 1 · Structure
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PB830
RIP1 Inhibitor
PB830 is a potent receptor interacting protein 1 (RIP1) inhibitor, exhibiting an IC50 of less than 100 nM for human RIP1. It demonstrates significant biological activity with an EC50 ranging from 1 to 100 nM in cell necrosis assays. This compound is primarily utilized in research focusing on cell death pathways and the modulation of necroptosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2428401-23-2 |
| Applications | RIP1 Inhibitor |
| Formula | C20H20FN3O |
| Molecular Weight | 337.39 |
| SMILES | O=C(N1CC(C1)CC2=CC(F)=CC=C2)N3N=CCC3C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.