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PBA-1106

AUTOTAC

PBA-1106 is an autophagy-targeting chimera (AUTOTAC) that promotes p62 self-oligomerization. By enhancing the autophagic flux of ubiquitin-conjugated aggregates, PBA-1106 aids in the selective degradation of protein aggregates. This compound is useful for research in autophagy regulation and cellular proteostasis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2410081-55-7
Applications	AUTOTAC
Formula	C₄₁H₅₂N₂O₈
Molecular Weight	700.86
SMILES	O[C@H](CNCCOCCOCCOCCNC(CCCC1=CC=CC=C1)=O)COC2=CC(OCC3=CC=CC=C3)=C(OCC4=CC=CC=C4)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.