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PBD derivative-1

PBD Derivative

PBD derivative-1 is a synthetic derivative of the potent DNA-targeting agent PBD, primarily utilized in the development of antibody-drug conjugates (ADCs). This compound is instrumental in the synthesis of ADCs, providing effective delivery of cytotoxic agents directly to tumor cells. Its application in cancer research highlights its potential for enhancing therapeutic efficacy and specificity in targeted cancer therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2305851-17-4
Applications	PBD Derivative
Formula	C₄₀H₄₄N₄O₇
Molecular Weight	692.80
SMILES	O=C1N2CC3(CC3)C[C@@]2([H])C=NC4=CC(OCCCCCOC5=C(C=C6C(NC[C@@]7([H])N(C=C(C8=CC=C(C=C8)OC)C7)C6=O)=C5)OC)=C(OC)C=C41

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.