PBD-monoamide, a modified pyrrolobenzodiazepine (PBD) dimer, serves as an antibody-drug conjugate (ADC) cytotoxin. This compound exhibits DNA-binding activity, leading to reduced cell viability, making it a valuable tool for cancer research. PBD-monoamide is utilized in the synthesis of DHES0815A, an ADC targeting HER2, facilitating the study of targeted cancer therapies.
PBD-monoamide, a modified pyrrolobenzodiazepine (PBD) dimer, serves as an antibody-drug conjugate (ADC) cytotoxin. This compound exhibits DNA-binding activity, leading to reduced cell viability, making it a valuable tool for cancer research. PBD-monoamide is utilized in the synthesis of DHES0815A, an ADC targeting HER2, facilitating the study of targeted cancer therapies.
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