Fig. 1 · Structure

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PBR28

TSPO Modulator

PBR28 is a potent modulator of the translocator protein (TSPO), primarily engaged in research related to Pulmonary Arterial Hypertension (PAH). This compound facilitates the tracking of the 18 kDa TSPO through radioactive labeling, making it a valuable tool in brain positron emission tomography (PET) imaging studies. Its unique properties can provide insights into various biological processes and aid in the development of therapeutic strategies targeting TSPO-related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 253307-65-2
Applications TSPO Modulator
Formula C21H20N2O3
Molecular Weight 348.40
SMILES
O=C(C)N(CC1=C(OC)C=CC=C1)C2=C(OC3=CC=CC=C3)C=CN=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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