Fig. 1 · Structure
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PBT 1033 hydrochloride
Copper/Zinc Ionophore
PBT 1033 hydrochloride is an orally active copper/zinc ionophore that plays a significant role in the modulation of metal ion transport. It has been shown to restore cognitive function in mouse models of Alzheimer's disease, suggesting its potential for neuroprotective applications. Additionally, PBT 1033 exhibits antibacterial activity against Gram-positive bacteria, making it a valuable tool for research in both neurobiology and microbiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 648896-70-2 |
| Applications | Copper/Zinc Ionophore |
| Formula | C12H13Cl3N2O |
| Molecular Weight | 307.60 |
| Synonyms | PBT 2 hydrochloride |
| SMILES | OC1=C2N=C(C=CC2=C(C=C1Cl)Cl)CN(C)C.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.