PBT434 mesylate is an orally active α-synuclein aggregation inhibitor that effectively penetrates the blood-brain barrier. This compound functions as an iron chelator, modulating transcellular iron trafficking while inhibiting iron-mediated redox activity and the aggregation of α-synuclein. PBT434 mesylate demonstrates neuroprotective effects by preventing the loss of neurons in the substantia nigra pars compacta. It holds promise for advancing research in Parkinson’s disease.
PBT434 mesylate is an orally active α-synuclein aggregation inhibitor that effectively penetrates the blood-brain barrier. This compound functions as an iron chelator, modulating transcellular iron trafficking while inhibiting iron-mediated redox activity and the aggregation of α-synuclein. PBT434 mesylate demonstrates neuroprotective effects by preventing the loss of neurons in the substantia nigra pars compacta. It holds promise for advancing research in Parkinson’s disease.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
