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PCAF/GCN5 ligand 1

PCAF/GCN5 Ligand

PCAF/GCN5 Ligand 1 is a selective ligand targeting the PCAF/GCN5 histone acetyltransferases, boasting high binding affinity. Although it does not exert a functional effect on PCAF/GCN5 activity, it serves as a valuable tool for exploring the role of these proteins in chromatin regulation. Additionally, PCAF/GCN5 Ligand 1 is a precursor for the development of more potent ligands, such as GSK4027, facilitating advancements in epigenetic research and therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1209224-91-8
Applications	PCAF/GCN5 Ligand
Formula	C₁₂H₁₁ClFN₃O
Molecular Weight	267.69
SMILES	CN1N=CC(NCC2=CC=C(F)C=C2)=C(Cl)C1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.