Fig. 1 · Structure
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PCNA-IN-1
PCNA Inhibitor
PCNA-IN-1 is a selective inhibitor of the PCNA/PIP-box interaction, demonstrating an IC50 greater than 50 μM. This compound is primarily utilized in cancer research, offering potential insights into the mechanisms of cell proliferation and tumor progression. Its ability to disrupt protein interactions makes it a valuable tool for studying the role of PCNA in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1417653-45-2 |
| Applications | PCNA Inhibitor |
| Formula | C19H18I3NO3 |
| Molecular Weight | 689.06 |
| SMILES | IC1=C(OC2=CC=C(O)C(I)=C2)C(I)=CC(CC(N3CCCCC3)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.