Fig. 1 · Structure

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PCSK9 ligand 2

Target Protein Ligand

PCSK9 ligand 2 functions as a target protein ligand for PROTAC PCSK9 autophagic degrader 2, facilitating the selective degradation of PCSK9. This compound plays a vital role in lowering cholesterol levels by enhancing the clearance of LDL receptors, making it useful in anti-atherosclerosis research. Its application can aid in the development of novel therapeutic strategies aimed at cardiovascular diseases associated with lipid metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3039841-82-9
Applications Target Protein Ligand
Formula C16H19N3O3S
Molecular Weight 333.41
SMILES
O=C(NC1=NC=CS1)CC2(C)NCCC3=C2C=C(O)C(OC)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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