PD-1/PD-L1-IN-13 is a potent inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 value of 10.2 nM. This compound effectively promotes CD8+ T cell activation, enhancing anti-tumor immunity. Its application in preclinical models, such as the Hepa1-6 syngeneic mouse model, demonstrates its potential to delay tumor growth, making it valuable for research in immunotherapy and cancer biology.
PD-1/PD-L1-IN-13 is a potent inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 value of 10.2 nM. This compound effectively promotes CD8+ T cell activation, enhancing anti-tumor immunity. Its application in preclinical models, such as the Hepa1-6 syngeneic mouse model, demonstrates its potential to delay tumor growth, making it valuable for research in immunotherapy and cancer biology.
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