PD-1/PD-L1-IN-14 is a bifunctional inhibitor specifically targeting the PD-1/PD-L1 interaction, exhibiting an IC50 of 27.8 nM. This compound effectively disrupts PD-1/PD-L1 binding while promoting the dimerization, internalization, and degradation of PD-L1. Its unique mechanism of action supports research in immunotherapy and cancer treatment, making it a valuable tool for studies involving immune modulation and T-cell activation.
PD-1/PD-L1-IN-14 is a bifunctional inhibitor specifically targeting the PD-1/PD-L1 interaction, exhibiting an IC50 of 27.8 nM. This compound effectively disrupts PD-1/PD-L1 binding while promoting the dimerization, internalization, and degradation of PD-L1. Its unique mechanism of action supports research in immunotherapy and cancer treatment, making it a valuable tool for studies involving immune modulation and T-cell activation.
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