PD-1/PD-L1-IN-17

Catalog No.: A35736
PD-1/PD-L1 Inhibitor
PD-1/PD-L1-IN-17 is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 26.8 nM. This compound serves as a valuable lead in the development of PD-1/PD-L1 inhibitors, making it an important tool for cancer research. Its ability to modulate immune checkpoint pathways highlights its potential in the exploration of cancer immunotherapy strategies.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPD-1/PD-L1-IN-17 is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 26.8 nM. This compound serves as a valuable lead in the development of PD-1/PD-L1 inhibitors, making it an important tool for cancer research. Its ability to modulate immune checkpoint pathways highlights its potential in the exploration of cancer immunotherapy strategies.
Product Information
Catalog NumA35736
FormulaC23H20ClN3O4
Molecular Weight437.88
CAS Number2851938-36-6
SMILESO=C([C@H](CO)NCC1=CC2=C(ON=C2NC3=CC=CC(C4=CC=CC=C4)=C3Cl)C=C1)O
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