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PD-1/PD-L1-IN-21

PD-1/PD-L1 Inhibitor

PD-1/PD-L1-IN-21 is a small-molecule inhibitor targeting the PD-1/PD-L1 protein-protein interaction, exhibiting an IC50 of 4.99 μM. This compound effectively blocks PD-1 and PD-L1, making it a valuable tool for research into cancer, infectious diseases, and autoimmune conditions. Its ability to disrupt this immune checkpoint pathway positions PD-1/PD-L1-IN-21 as a significant reagent for studies aimed at enhancing anti-tumor immunity and understanding immune responses.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2158336-16-2
Applications	PD-1/PD-L1 Inhibitor
Formula	C₃₂H₃₂BrClN₂O₄
Molecular Weight	623.96
SMILES	CC[C@H](C)[C@@H](C(O)=O)NCC(C=C(C(OCC1=C(C(C2=CC=CC=C2)=CC=C1)Br)=C3)Cl)=C3OCC4=CN=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.