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PD-1/PD-L1-IN-24

PD-1/PD-L1 Inhibitor

PD-1/PD-L1-IN-24 is a potent inhibitor of the PD-1/PD-L1 pathway, exhibiting an IC50 value of 1.57 nM. This compound effectively restores T-cell function by significantly increasing the levels of IFN-γ at the cellular level. With low toxicity towards peripheral blood mononuclear cells (PBMCs), PD-1/PD-L1-IN-24 is suitable for research applications focused on cancer immunotherapy and autoimmunity studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2667680-33-1
Applications	PD-1/PD-L1 Inhibitor
Formula	C₃₄H₃₀ClN₅O₆
Molecular Weight	640.08
SMILES	N#CC1=CN=CC(COC2=CC(OC3=NC=NC4=C3C=CC=C4C5=CC6=C(OCCO6)C=C5)=C(C=C2CNC(CO)(CO)C)Cl)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.