PD-1/PD-L1-IN-27 is a potent inhibitor of the PD-1/PD-L1 pathway, demonstrating an IC50 value of 134 nM. This compound exhibits significant antitumor activity while maintaining low cytotoxicity towards T cells. Additionally, PD-1/PD-L1-IN-27 effectively activates CD8+ T cells and mitigates T cell exhaustion, making it a valuable tool for immuno-oncology research applications.
PD-1/PD-L1-IN-27 is a potent inhibitor of the PD-1/PD-L1 pathway, demonstrating an IC50 value of 134 nM. This compound exhibits significant antitumor activity while maintaining low cytotoxicity towards T cells. Additionally, PD-1/PD-L1-IN-27 effectively activates CD8+ T cells and mitigates T cell exhaustion, making it a valuable tool for immuno-oncology research applications.
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