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PD-1/PD-L1-IN-31

PD-1/PD-L1 Inhibitor

PD-1/PD-L1-IN-31 is a potent inhibitor of the PD-1/PD-L1 pathway, demonstrating an IC50 value of 2.2 nM. This compound enhances the secretion of interferon-gamma (IFN-γ) and stimulates the immune response of peripheral blood mononuclear cells (PBMCs), leading to the inhibition of tumor cell proliferation. PD-1/PD-L1-IN-31 is valuable for research applications focused on cancer immunotherapy and the modulation of immune checkpoints.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3049472-36-5
Applications	PD-1/PD-L1 Inhibitor
Formula	C₂₄H₂₄ClFN₂O₃
Molecular Weight	442.91
SMILES	FC1=CC=CC=C1C2=CC=CC3=C2CC[C@@H]3OC4=NC(OC)=C(CNCCO)C=C4Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.