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PD-1/PD-L1-IN 5 TFA

PD-1/PD-L1 Inhibitor

PD-1/PD-L1-IN 5 TFA is a potent inhibitor of the PD-1/PD-L1 protein-protein interaction, with an IC50 of ≤100 nM. This compound is beneficial for research applications focused on immune checkpoint modulation, particularly in the context of cancer immunotherapy. By blocking the PD-1/PD-L1 pathway, it aids in the investigation of T-cell activation and tumor immune evasion mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2170209-52-4
Applications	PD-1/PD-L1 Inhibitor
Formula	C₂₂H₁₈N₄O₃S.xC₂HF₃O₂
SMILES	N#CC1=C(NC(C2=NC3=C(CNCC3)S2)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4.OC(C(F)(F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.