Fig. 1 · Structure

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PD-1/PD-L1-IN-55

PD-1/PD-L1 Inhibitor

PD-1/PD-L1-IN-55 is a potent inhibitor targeting the PD-1/PD-L1 immune checkpoint pathway, exhibiting an IC50 of 4.8 nM. This compound enhances the secretion of IFN-γ and decreases the incidence of late apoptosis in PD-L1 expressing cells. PD-1/PD-L1-IN-55 is valuable for research applications in cancer therapy and immunology, particularly in studies aimed at restoring T-cell activation and modulating immune responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3052262-83-3
Applications PD-1/PD-L1 Inhibitor
Formula C25H23ClN2O3
Molecular Weight 434.91
SMILES
C[C@H](N)C(N1CC2=CC(C3=C(C(C4=CC=C(OCCO5)C5=C4)=CC=C3)Cl)=CC=C2C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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