Fig. 1 · Structure

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PD-1/PD-L1-IN-59

PD-1/PD-L1 Inhibitor

PD-1/PD-L1-IN-59 is a PD-1/PD-L1 inhibitor with an IC50 value of 183 nM. This compound is instrumental in the investigation of immune checkpoint regulation and has significant potential for research applications in triple-negative breast cancer (TNBC) therapies. By blocking the PD-1/PD-L1 interaction, it fosters immune response against tumor cells and facilitates the exploration of novel immunotherapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2891831-40-4
Applications PD-1/PD-L1 Inhibitor
Formula C35H31NO7
Molecular Weight 577.62
SMILES
O=C1OC2=CC=CC=C2C(OC3=C(C=CC(OCC4=C(C(C5=CC=CC=C5)=CC=C4)C)=C3)CN6[C@@H](C[C@H](C6)O)C(O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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