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PD-1/PD-L1-IN-60

PD-L1 Inhibitor

PD-1/PD-L1-IN-60 is an inhibitor of PD-L1, a key checkpoint protein involved in immune evasion of tumors. This compound demonstrates significant anti-tumor activity in preclinical models, particularly within melanoma and lung cancer contexts where PD-L1 expression is elevated. PD-1/PD-L1-IN-60 is suitable for research applications focused on immunotherapy, tumor immune microenvironment studies, and the evaluation of therapeutic strategies targeting PD-L1.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3095344-37-6
Applications	PD-L1 Inhibitor
Formula	C₅₃H₇₀ClFN₄O₁₅
Molecular Weight	1057.59
SMILES	OCC(CO)(CO)N(CC1=CN(CCOCCOCCOCCOCCOCCOCCOCCF)N=N1)CC(C(OCC2=CC(O)=CC=C2)=C3)=CC(Cl)=C3OCC4=C(C)C(C5=CC6=C(OCCO6)C=C5)=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.