Fig. 1 · Structure
Documents & Downloads
PD-1/PD-L1-IN-9
PD-1/PD-L1 Interaction Inhibitor
PD-1/PD-L1-IN-9 is a potent inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 value of 3.8 nM. This compound enhances the antitumor activity of immune cells against tumor cells. Additionally, PD-1/PD-L1-IN-9 demonstrates significant in vivo antitumor efficacy in the CT26 mouse model, making it a valuable tool for cancer immunotherapy research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2628506-54-5 |
| Applications | PD-1/PD-L1 Interaction Inhibitor |
| Formula | C22H24N2O2 |
| Molecular Weight | 348.44 |
| SMILES | CC1=C(C=CC=C1C2=CC=CC=C2)C3=NC(OC)=C(C=C3)CNCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.