Fig. 1 · Structure
Documents & Downloads
PD-1/PD-L1-IN-NP19
PD-1/PD-L1 Inhibitor
PD-1/PD-L1-IN-NP19 is a potent inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 12.5 nM. This compound is designed to enhance immune responses within the tumor microenvironment, potentially leading to significant antitumor activity. It is a valuable tool for researchers investigating immunotherapy and the modulation of immune checkpoints in cancer therapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2377916-66-8 |
| Applications | PD-1/PD-L1 Inhibitor |
| Formula | C33H31ClN2O4 |
| Molecular Weight | 555.06 |
| SMILES | CC(C)(NCC1=CC(Cl)=C(OCC2=C(C)C(C3=CC=CC=C3)=CC=C2)C=C1OCC4=CC=CC(C#N)=C4)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.