Fig. 1 · Structure
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PD 118440
Dopamine Agonist
PD 118440 is an orally active dopamine agonist that targets dopaminergic signaling pathways within the central nervous system. This compound demonstrates notable biological activity by inhibiting striatal dopamine synthesis and suppressing the firing of dopamine neurons. Additionally, PD 118440 has been shown to reverse Reserpine-induced depression in rodent models, making it a valuable tool for research in neuropharmacology and mood disorder studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 108351-90-2 |
| Applications | Dopamine Agonist |
| Formula | C11H17N3S |
| Molecular Weight | 223.34 |
| SMILES | NC1=NC(C2=CCCN(C2)CCC)=CS1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.