Documents & Downloads

PD-143188

DA Receptor Agonist

PD-143188 is a selective agonist of dopamine (DA) receptors, exhibiting Ki values of 25.5 nM for human D2 receptors and 16.6 nM for D3 receptors, while demonstrating lower affinity for D4.2 receptors (Ki=90.9 nM). This compound inhibits dopamine release, synthesis, and metabolism, leading to a reduction in cellular cyclic AMP levels, and demonstrates potential antipsychotic activity. PD-143188 is valuable for research in psychopharmacology and the exploration of dopamine-related pathways in neurological studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	150013-70-0
Applications	DA Receptor Agonist
Formula	C₂₄H₂₇N
Molecular Weight	329.48
Synonyms	CI 1007
SMILES	C1(C2=CC=CC=C2)=CCN(C[C@H]3CC(C4=CC=CC=C4)=CCC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.