Fig. 1 · Structure
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PD 165929
NMB Receptor Antagonist
PD 165929 is a selective, high-affinity non-peptide antagonist for the neuromedin-B (NMB) receptor, demonstrating a Ki value of 6.3 nM and an IC50 of 150 nM in rat models. This compound is valuable for investigating the physiological roles of NMB signaling and its implications in neurobiology and related disorders. Its specificity and potency make it an essential tool for research focused on receptor pharmacology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 185215-75-2 |
| Applications | NMB Receptor Antagonist |
| Formula | C37H47N5O2 |
| Molecular Weight | 593.80 |
| SMILES | CC(C)C(C=CC=C1C(C)C)=C1NC(N[C@](CC2=CNC3=CC=CC=C23)(C)C(NCC4(C5=CC=CC=N5)CCCCC4)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.