Fig. 1 · Structure

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PD-168077

Dopamine Receptor Agonist

PD-168077 is a selective agonist for the dopamine D4 receptor, exhibiting a binding affinity (Ki) of 9 nM. This compound demonstrates significant biological activity in modulating dopaminergic signaling pathways, making it a useful tool for research focused on neuropharmacology and psychiatric disorders. Its specificity for the D4 receptor allows for targeted studies in areas such as schizophrenia and addiction, facilitating the exploration of therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 190383-31-4
Applications Dopamine Receptor Agonist
Formula C20H22N4O
Molecular Weight 334.41
SMILES
O=C(NCN1CCN(C2=CC=CC=C2C#N)CC1)C3=CC=CC(C)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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