PD-L1-IN-1 is a potent inhibitor targeting programmed cell death ligand 1 (PD-L1) with an IC50 of 115 nM. It effectively disrupts the PD-L1 and PD-1 interaction, enhancing antitumor immune responses in co-cultures of PD-L1 expressing cancer cells and peripheral blood mononuclear cells. Additionally, PD-L1-IN-1 demonstrates low cytotoxicity towards healthy cells, making it a valuable tool for immunological research and therapeutic applications in cancer treatment.
PD-L1-IN-1 is a potent inhibitor targeting programmed cell death ligand 1 (PD-L1) with an IC50 of 115 nM. It effectively disrupts the PD-L1 and PD-1 interaction, enhancing antitumor immune responses in co-cultures of PD-L1 expressing cancer cells and peripheral blood mononuclear cells. Additionally, PD-L1-IN-1 demonstrates low cytotoxicity towards healthy cells, making it a valuable tool for immunological research and therapeutic applications in cancer treatment.
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