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PD-L1-IN-5

PD-L1 Inhibitor

PD-L1-IN-5 is a potent inhibitor of programmed death-ligand 1 (PD-L1), exhibiting an IC50 value of 785.6 nM. This compound demonstrates significant anti-tumor activity in vivo, making it a valuable tool for cancer research. PD-L1-IN-5 is utilized in studies focusing on immune checkpoint regulation and therapeutic strategies aimed at enhancing anti-tumor immunity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2597056-85-2
Applications	PD-L1 Inhibitor
Formula	C₄₀H₄₄ClFN₄O₈
Molecular Weight	763.25
SMILES	OC1CCN(CCCOC2=CC=CC(C3=CC=CC(COC4=C(Cl)C=C(CN[C@@H](C(OCC)=O)CO)C(OCC5=CC6=NON=C6C=C5)=C4)=C3F)=C2)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.