Fig. 1 · Structure
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PD159790
ECE-1 Inhibitor
PD159790 is a selective inhibitor of endothelin-converting enzyme-1 (ECE-1), demonstrating an EC50 of 28.1 μM. This compound plays a critical role in modulating endothelin levels, making it valuable for research into cardiovascular and pulmonary diseases. Its application extends to investigations of ECE-1's role in pathophysiological processes, contributing to a deeper understanding of related therapeutic targets.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 179598-53-9 |
| Applications | ECE-1 Inhibitor |
| Formula | C16H18F3IN4 |
| Molecular Weight | 450.24 |
| SMILES | FC(F)(F)C1=NC(NC2CN(CCC2)CC)=C3C=C(C=CC3=N1)I |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.