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| Description | PD168393 is a potent, cell-permeable, irreversible inhibitor of EGFR with IC50 value of 700 pM. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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| Catalog Num | A12725 |
|---|---|
| Formula | C17H13BrN4O |
| Molecular Weight | 369.22 |
| CAS Number | 194423-15-9 |
| SMILES | C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br |
| Synonyms | PD-168393, PD 168393 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 72 mg/mL (195 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 9 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.08 mL | 135.42 mL | 270.84 mL |
| 0.5 mM | 5.42 mL | 27.08 mL | 54.17 mL |
| 1 mM | 2.71 mL | 13.54 mL | 27.08 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.42 mL |
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
