PD168393

Catalog No.: A12725

EGFR inhibitor

PD168393 Chemical Structure

CAS NO. 194423-15-9

PD168393 is a potent, cell-permeable, irreversible inhibitor of EGFR with IC50 value of 700 pM.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$110.00
50 mg
$250.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PD168393 is a potent, cell-permeable, irreversible inhibitor of EGFR with IC50 value of 700 pM.
Targets
EGFR Insulin Receptor PDGFR FGFR PKC
0.70 nM>50 μM>50 μM>50 μM>50 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.08 mL 135.42 mL 270.84 mL
0.5 mM 5.42 mL 27.08 mL 54.17 mL
1 mM 2.71 mL 13.54 mL 27.08 mL
5 mM 0.54 mL 2.71 mL 5.42 mL

*The above data is based on the productmolecular weight 369.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12725
Actions Inhibitor
M. Wt 369.22
Formula C17H13BrN4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 194423-15-9
Synonyms PD-168393, PD 168393
SMILES C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br

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