Fig. 1 · Structure
Documents & Downloads
PDK1/AurA-IN-1
Drug Derivative
PDK1/AurA-IN-1 is an inhibitor targeting PDK1 (3-phosphoinositide dependent protein kinase-1) and AurA (Aurora kinase A). This compound exhibits potent inhibitory activity, making it a valuable tool in elucidating the role of these kinases in cell cycle regulation and cancer progression. It is primarily utilized in research applications associated with cancer biology, particularly in studying cancer cell proliferation and therapeutic resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1919884-11-9 |
| Applications | Drug Derivative |
| Formula | C33H24F2N6O4 |
| Molecular Weight | 606.58 |
| SMILES | O=C(N[C@@H](C(NC1=CC2=C(C=C1)NC(/C2=C\C3=CN=CN3)=O)=O)C4=CC=CC=C4)C5=CC=CN(C5=O)CC6=CC=C(C(F)=C6)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.