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PDK4-IN-2

PDK4 Inhibitor

PDK4-IN-2 is a selective inhibitor of pyruvate dehydrogenase kinase 4 (PDK4) with an IC50 of 46 µM. It has demonstrated the ability to enhance ejection fraction in failing hearts by modulating bioenergetics through the activation of the tricarboxylic acid cycle. This compound is valuable for research into cardiac metabolism and potential therapeutic strategies for heart failure.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1616752-12-5
Applications	PDK4 Inhibitor
Formula	C₁₃H₁₀O₅
Molecular Weight	246.22
SMILES	COC(C1=CC2=C(C(O)=C1)C(C=C(C2=O)C)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.