Fig. 1 · Structure

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Pefloxacin-d3

Stable Isotope

Pefloxacin-d3 is a deuterated derivative of the broad-spectrum antibiotic Pefloxacin, designed for stable isotope research applications. It primarily targets DNA gyrase, inhibiting DNA replication, and shows effective activity against various bacterial strains including Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis, with MIC90 values of 0.12, 4, and 16 mg/L, respectively. Additionally, Pefloxacin exhibits anti-Plasmodium yoelii activity and can enhance UVA-induced edema and immunosuppression. This reagent is suitable for infection studies and advanced biochemical assays.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2733455-58-6
Applications Stable Isotope
Formula C17H17D3FN3O3
Molecular Weight 336.38
Synonyms Pefloxacinium-d3
SMILES
O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCN(C([2H])([2H])[2H])CC3)=C2)C1=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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