Fig. 1 · Structure
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Pefloxacin-d5
Stable Isotope
Pefloxacin-d5 is a deuterated derivative of Pefloxacin, functioning primarily as a stable isotope for various research applications. This broad-spectrum antibiotic acts by inhibiting DNA gyrase, subsequently blocking DNA replication. Pefloxacin demonstrates antibacterial efficacy against pathogens such as Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis, with respective MIC90s of 0.12, 4, and 16 mg/L. Additionally, it exhibits activity against Plasmodium yoelii and may enhance UVA-induced edema and immunosuppression, rendering it valuable for infection and pharmacological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1228182-51-1 |
| Applications | Stable Isotope |
| Formula | C17H15D5FN3O3 |
| Molecular Weight | 338.39 |
| Synonyms | Pefloxacinium-d5 |
| SMILES | O=C(C1=CN(C([2H])([2H])C([2H])([2H])[2H])C2=C(C=C(F)C(N3CCN(C)CC3)=C2)C1=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.