Peganumine A

Catalog No.: B19211
Natural Product
Peganumine A is a natural product derived from Peganum harmala, primarily known for its cytotoxic effects. It exhibits cytotoxicity with IC50 values of 5.8 µM for HL-60, 38.5 µM for MCF-7, 40.2 µM for PC-3, and 55.4 µM for HepG2 cell lines. This compound is of interest in cancer research for its potential therapeutic applications and mechanisms of action in targeting cell viability.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPeganumine A is a natural product derived from Peganum harmala, primarily known for its cytotoxic effects. It exhibits cytotoxicity with IC50 values of 5.8 µM for HL-60, 38.5 µM for MCF-7, 40.2 µM for PC-3, and 55.4 µM for HepG2 cell lines. This compound is of interest in cancer research for its potential therapeutic applications and mechanisms of action in targeting cell viability.
Product Information
Catalog NumB19211
FormulaC29H30N4O3
Molecular Weight482.57
CAS Number1620517-85-2
SMILESCOC1=CC(N2)=C(C=C1)C3=C2[C@]45N(CC3)C([C@]6(C(C)(C)C5)C7=C(C8=CC=C(OC)C=C8N7)CCN64)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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