Fig. 1 · Structure
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Pegaptanib sodium
Anti-VEGF Agent
Pegaptanib sodium is an RNA aptamer modified with polyethylene glycol, specifically targeting vascular endothelial growth factor (VEGF)-165. This compound exhibits biological activity by inhibiting angiogenesis, making it particularly relevant for research in neovascular age-related macular degeneration (AMD). Pegaptanib sodium serves as a valuable tool for investigating therapeutic strategies in ocular diseases characterized by aberrant vascular growth.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 222716-86-1 |
| Applications | Anti-VEGF Agent |
| Molecular Weight | 50000 (Approximately) |
| Synonyms | EYE001; NX1838 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.