Fig. 1 · Structure
Documents & Downloads
(-)-Penbutolol (l-Penbutolol)
β-Adrenoceptor Antagonist
(-)-Penbutolol is a potent β-adrenoceptor antagonist exhibiting an affinity with a Ki value of 11.6 nM for β-adrenoceptors and 11.9 nM for 5-HT receptors in both rat cornu ammonis 1 (CA1) and human CA3 regions. This compound is instrumental in studies involving cardiovascular research and neuropharmacology, particularly in understanding the modulation of adrenergic and serotonergic signaling pathways. Its dual receptor targeting makes it valuable for exploring therapeutic interventions for conditions such as hypertension and anxiety disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 38363-40-5 |
| Applications | β-Adrenoceptor Antagonist |
| Formula | C18H29NO2 |
| Molecular Weight | 291.43 |
| Synonyms | (S)-Penbutolol; (-)-Isopenbutolol; l-Penbutolol |
| SMILES | O[C@H](COC1=CC=CC=C1C2CCCC2)CNC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.