Fig. 1 · Structure
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Penicinoline
Secondary Metabolite
Penicinoline, a pyrrolyl 4-quinolinone alkaloid, acts as a secondary metabolite derived from the endophytic fungus Penicillium sp. This compound exhibits potent antimalarial activity against both Chloroquine-sensitive (pf3d7) and Chloroquine-resistant (pfDd2) strains of Plasmodium falciparum. Additionally, Penicinoline demonstrates strong insecticidal properties against Aphis gossypii and shows selective anticancer effects with significant cytotoxicity in 95-D and HepG2 cell lines, making it a valuable tool for research in parasitology, entomology, and oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1214268-60-6 |
| Applications | Secondary Metabolite |
| Formula | C14H10N2O3 |
| Molecular Weight | 254.24 |
| Synonyms | Marinamide |
| SMILES | O=C(C1=C(C2=CC=CN2)NC3=C(C=CC=C3)C1=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.