Fig. 1 · Structure
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Pentagalloylglucose
Antioxidant
Pentagalloylglucose is a gallic tannin compound with potent antioxidant properties that plays a critical role in cellular apoptosis and autophagy. It acts through the GSK3β/β-catenin signaling pathway, effectively inhibiting UBE2T-mediated p53 ubiquitination, leading to the upregulation of p53 and downregulation of RRM1/RRM2 in pancreatic cancer organoids. This versatile compound also exhibits anti-inflammatory, anti-mutagenic, anticonvulsant, cardioprotective, cholesterol-lowering, and anti-tumor activities, making it valuable for various research applications in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 14937-32-7 |
| Applications | Antioxidant |
| Formula | C41H32O26 |
| Molecular Weight | 940.68 |
| Synonyms | Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose |
| SMILES | O=C(C1=CC(O)=C(O)C(O)=C1)O[C@@H]([C@@H]([C@@H](COC(C2=CC(O)=C(O)C(O)=C2)=O)O3)OC(C4=CC(O)=C(O)C(O)=C4)=O)[C@H]([C@@H]3OC(C5=CC(O)=C(O)C(O)=C5)=O)OC(C6=CC(O)=C(O)C(O)=C6)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.